A 58-year-old man with a 10-year history of type 2 diabetes mellitus and hypertension presents with acute onset chest pain and dyspnea. ECG shows ST elevation in leads II, III, and aVF. Troponin I is 2.8 ng/mL (normal <0.04 ng/mL). He is taken for emergency coronary angiography, which reveals a thrombus in the right coronary artery. Aspiration thrombectomy is performed and the thrombus is sent for histopathology. Microscopy shows platelet-rich thrombus with minimal fibrin. What is the most likely mechanism underlying thrombus formation in this patient?
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