## Vaccines in Indian UIP: Core vs. Conditional **Key Point:** The Universal Immunisation Programme in India includes core vaccines that are administered universally to all children, while certain vaccines are conditionally recommended based on geographic prevalence or risk factors. ### Core UIP Vaccines (Universal) | Vaccine | Disease | Schedule | |---------|---------|----------| | BCG | Tuberculosis | Birth | | OPV/IPV | Poliomyelitis | Birth, 6, 10, 14 weeks, 18-24 months | | DPT (Pentavalent/Hexavalent) | Diphtheria, Pertussis, Tetanus | 6, 10, 14 weeks | | Measles-Rubella (MR) | Measles, Rubella | 9-12 months, 16-24 months | | Hepatitis B | Hepatitis B | Birth, 6, 10, 14 weeks | | Rotavirus | Rotavirus gastroenteritis | 6, 10, 14 weeks | | PCV (Pneumococcal) | Pneumococcal disease | 6, 10, 14 weeks | ### Conditional/State-Specific Vaccines (NOT in routine UIP) - **Japanese Encephalitis (JE) vaccine** — Administered in endemic states (Uttar Pradesh, Bihar, Assam, West Bengal, Jharkhand) - **Typhoid Conjugate Vaccine (TCV)** — Recommended in high-burden areas - **Varicella** — Not routinely included **High-Yield:** JE vaccine is a classic example of a vaccine that is epidemiologically important but conditionally included based on geographic prevalence. It is NOT part of the universal UIP schedule across India. **Clinical Pearl:** Diphtheria, Tetanus, and Pertussis are all components of the DPT/Pentavalent vaccine, which is a CORE UIP vaccine given to all children universally.
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