## UIP Schedule for Oral Polio Vaccine **Key Point:** The **first dose** of OPV (OPV-0) is administered at **birth** (within 24 hours, or up to 15 days of life) under the Universal Immunisation Programme of India. ### OPV Dosing Schedule in India | Age | Vaccine | Dose | | --- | --- | --- | | **Birth** | **BCG, OPV-0, Hepatitis B-0** | **First dose of OPV** | | 6 weeks | DPT-1, IPV-1, OPV-1, Hepatitis B-1, PCV-1, Rotavirus-1 | OPV-1 (primary series begins) | | 10 weeks | DPT-2, IPV-2, OPV-2, Hepatitis B-2, PCV-2, Rotavirus-2 | OPV-2 | | 14 weeks | DPT-3, IPV-3, OPV-3, Hepatitis B-3, PCV-3, Rotavirus-3 | OPV-3 | | 16-24 months | DPT-B, OPV-B, IPV-B | OPV Booster | **High-Yield:** The question asks for the **first dose** of OPV — this is OPV-0, given at **birth** (within 24 hours, ideally before discharge from the facility). The primary series (OPV-1) begins at 6 weeks, but that is the *second* dose of OPV, not the first. **Clinical Pearl:** OPV-0 at birth is a "zero dose" given to provide early mucosal immunity in the gut before the primary series begins. This is a commonly tested distinction in PSM/UIP questions — the *first* dose is at birth, while the *primary series* starts at 6 weeks. (Park's Textbook of Preventive and Social Medicine, 26th edition; Government of India UIP Schedule) **Mnemonic:** **ZERO at BIRTH** — OPV-0 (zero dose) is given at birth; the primary series (OPV-1, 2, 3) follows at 6, 10, and 14 weeks.
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