Genital Herpes

A 28-year-old woman presents to the dermatology clinic with a 3-day history of painful vesicles on the vulva and perianal region. She reports fever (38.5°C), dysuria, and severe pain. On examination, grouped vesicles on an erythematous base are seen, along with tender inguinal lymphadenopathy. She denies any prior similar episodes. Viral culture from the vesicular fluid is positive for HSV-2. What is the most appropriate management for this primary episode of genital herpes?

A 32-year-old man with a history of genital herpes presents with recurrent episodes of painful vesicles on the penis occurring 4–5 times per year, each lasting 7–10 days. He reports prodromal tingling 12–24 hours before lesion onset. He is concerned about transmission to his partner and requests long-term management. What is the most appropriate strategy to reduce recurrence frequency and transmission risk?

A 28-year-old woman presents to the dermatology clinic with a 3-day history of painful vesicles on the vulva and perianal region. She reports severe pain, dysuria, and fever (38.2°C). On examination, grouped vesicles on an erythematous base are noted, along with tender inguinal lymphadenopathy. This is her first episode. She denies prior similar lesions. What is the most appropriate initial management?

A 32-year-old man with a history of genital herpes presents with recurrent lesions on the penile shaft for the third time in 6 months. He reports prodromal tingling and burning for 12 hours before vesicles appeared. On examination, grouped vesicles and erosions are seen. He is otherwise healthy and immunocompetent. Which of the following is the most appropriate management strategy for this recurrent episode?