1 MCQs in Medicine for NEET PG
A 28-year-old woman with a 2-year history of chronic diarrhea, right lower quadrant pain, weight loss, and oral aphthae undergoes ileocolonoscopy. The procedure reveals a tight asymmetric stricture in the terminal ileum with proximal pre-stenotic dilation, cobblestone mucosa, and deep linear ulcerations. Biopsies show transmural inflammation with non-caseating granulomas. The structure marked **A** in the diagram represents the tight luminal stricture. Which of the following best describes the pathophysiological mechanism underlying the formation of this stricture in Crohn disease?
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