Thyroid and Antithyroid Drugs

A 32-year-old woman with Graves' disease is started on propylthiouracil (PTU) therapy. After 6 weeks of treatment, she develops fever, sore throat, and a petechial rash. Her WBC count is 2,100/μL with severe neutropenia. Which investigation is most appropriate to confirm the suspected drug-induced complication?

All of the following statements regarding propylthiouracil (PTU) are correct EXCEPT:

A 35-year-old man with newly diagnosed Graves' disease is started on antithyroid therapy. He develops a diffuse maculopapular rash on day 10 of treatment. Liver function tests are normal, and there is no fever or lymphadenopathy. What is the most appropriate next step in management?

A 28-year-old woman with Graves' disease is 8 weeks pregnant and requires antithyroid therapy. Regarding drug selection and adverse effects of antithyroid agents, all of the following are true EXCEPT:

A 28-year-old woman with newly diagnosed Graves' disease is counseled about antithyroid therapy. She is planning pregnancy within 6 months and has no history of drug allergies. Which antithyroid drug is the preferred first-line choice for her?