Frontotemporal and Lewy Body Dementia

A 58-year-old man is brought by his wife with a 2-year history of progressive behavioral changes. He has become increasingly disinhibited, making inappropriate comments at social gatherings and engaging in compulsive eating of sweets despite being diabetic. His wife reports he no longer shows concern about his appearance or family responsibilities. Neurological examination reveals mild pyramidal signs in the lower limbs. MRI brain shows prominent frontal and anterior temporal lobe atrophy. Mini-Cog is 2/3, but he performs well on visuospatial tasks. What is the most likely diagnosis?

A 72-year-old woman presents with a 3-year history of progressive cognitive decline and parkinsonism. Her family reports she has become increasingly confused and forgetful, with frequent episodes of visual hallucinations of people and animals. She has developed a shuffling gait and resting tremor. Examination reveals bradykinesia, rigidity, and postural instability. Cognitive testing shows impairment in attention and visuospatial function with relative preservation of language. MRI brain shows generalized cerebral atrophy without focal lobar predominance. What is the most likely diagnosis?

A 58-year-old man from Delhi presents with a 2-year history of progressive personality change and socially inappropriate behaviour. His wife reports he has become disinhibited, making crude jokes at family gatherings, and has lost interest in his accounting job despite being previously meticulous. He occasionally forgets recent conversations but can recall distant memories clearly. On examination, he is alert and oriented but shows poor impulse control. Mini-Cog score is 24/30. MRI brain shows selective atrophy of the anterior temporal lobes bilaterally. What is the most likely diagnosis?

Which clinical feature is most characteristic of the behavioral variant of frontotemporal dementia (bvFTD)?

A 58-year-old man from Delhi presents to the psychiatry outpatient clinic with a 2-year history of progressive personality change and socially inappropriate behaviour. His wife reports he has become disinhibited, making crude jokes in public and spending money recklessly. Cognitive testing shows relatively preserved memory and orientation, but he scores poorly on executive function tasks. Neuroimaging reveals marked anterior temporal lobe atrophy, more pronounced on the left. What is the most likely diagnosis?