Acute Cholecystitis

A 52-year-old woman presents to the emergency department with severe right upper quadrant pain radiating to the right shoulder, nausea, and vomiting for 8 hours following a fatty meal. On examination, she has a fever of 38.5°C, RUQ tenderness with guarding, and a positive Murphy's sign. Ultrasound of the abdomen shows the findings marked as **B** in the diagram. Which of the following best describes the pathophysiological mechanism underlying the acute inflammation seen in this case?