Malignant Hyperthermia

A 35-year-old male with no significant past medical history undergoes elective knee arthroscopy under general anesthesia with propofol induction and sevoflurane maintenance. Intraoperatively, the patient develops unexplained tachycardia (HR 145/min), hypertension (BP 180/110 mmHg), muscle rigidity, and a core temperature of 39.2°C. Arterial blood gas shows pH 7.28, pCO₂ 58 mmHg, pO₂ 95 mmHg, and serum potassium 6.8 mEq/L. Which of the following is the MOST appropriate immediate management?

A 38-year-old woman is undergoing general anesthesia for elective thyroid surgery. After induction with propofol and intubation with succinylcholine, she develops sudden onset muscle rigidity, tachycardia (HR 130/min), hypertension (BP 160/95 mmHg), and a rise in end-tidal CO₂ (ETCO₂) from 35 to 55 mmHg within 10 minutes. Temperature is currently 37.2°C. Which of the following is the MOST appropriate immediate management?

A 35-year-old male patient is scheduled for elective abdominal surgery under general anesthesia. After induction with propofol and succinylcholine, the anesthesiologist observes a sustained increase in end-tidal CO₂ (ETCO₂) from 35 mmHg to 55 mmHg within 10 minutes, along with muscle rigidity and a rise in core body temperature. Which of the following is the most appropriate immediate management?

A 42-year-old male with a history of hypertension (on amlodipine) undergoes elective abdominal aortic aneurysm (AAA) repair under general anesthesia with endotracheal intubation. Intraoperatively, he receives succinylcholine 1.5 mg/kg IV for rapid sequence intubation. Within 2 minutes of drug administration, the anesthesiologist notes severe muscle rigidity, a core temperature of 38.5°C, and dark-colored urine in the catheter. Arterial blood gas shows pH 7.28, pCO₂ 52 mmHg, pO₂ 95 mmHg, and serum potassium 6.8 mEq/L. Which of the following is the MOST likely complication, and what is the immediate next step in management?

A 48-year-old male with a history of malignant hyperthermia (MH) susceptibility is scheduled for elective knee arthroscopy. Which of the following is the MOST appropriate anesthetic technique to minimize the risk of MH crisis?