The autoantibodies in Bullous Pemphigoid are primarily directed against which of the following components of the dermal-epidermal junction?
What is considered the first-line treatment for generalized Bullous Pemphigoid?
A skin biopsy from a patient suspected of having Bullous Pemphigoid is sent for direct immunofluorescence (DIF). Which of the following findings would confirm the diagnosis?
Histopathological examination of a tense bulla from a patient with Bullous Pemphigoid typically reveals which of the following features?
A 78-year-old male presents with a 3-month history of intensely pruritic, tense bullae on an erythematous and urticarial base, primarily affecting his trunk, flexural areas, and lower extremities. The lesions are difficult to rupture and a Nikolsky sign is absent. He denies any recent drug intake. Which of the following is the most likely diagnosis?
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