Bone Tumors

A 16-year-old male presents with progressive pain and swelling around his right knee for the past three months. X-rays reveal a lytic and sclerotic lesion in the distal femur with a 'sunburst' periosteal reaction and Codman's triangle. Which of the following is the most likely diagnosis?

A 7-year-old child presents with fever, localized pain, and swelling in the mid-shaft of the tibia. Radiographs show a lytic lesion with an 'onion-skin' periosteal reaction. Biopsy reveals small round blue cells. Which genetic translocation is most commonly associated with this tumor?

A 16-year-old male presents with progressive pain and swelling in his distal femur for 3 months. X-rays show a destructive lesion in the metaphysis with a 'sunburst' periosteal reaction and Codman's triangle. Which of the following is the most likely diagnosis?

A 30-year-old female presents with pain and swelling around her knee. X-rays reveal an eccentric, purely lytic lesion in the epiphysis of the distal femur, extending to the subarticular bone, without significant periosteal reaction. Histopathology shows multinucleated giant cells. What is the most probable diagnosis?

A 10-year-old boy presents with fever, localized pain, and swelling in his mid-shaft of the tibia. X-rays show a permeative lesion with a characteristic 'onion-skin' periosteal reaction. What is the most likely diagnosis?