Peptic Ulcer Disease

A 52-year-old man with a 10-year history of duodenal ulcer disease presents with epigastric pain and heartburn. Upper endoscopy confirms an active duodenal ulcer. He is H. pylori-positive on rapid urease test. What is the drug of choice for initial eradication therapy in this patient?

A 42-year-old man from Delhi presents with a 3-month history of epigastric pain relieved by food and antacids. Upper GI endoscopy reveals a 1.5 cm ulcer on the anterior wall of the first part of the duodenum with clean base. Which investigation is most appropriate to confirm the aetiology of this peptic ulcer?

A 52-year-old man from Delhi presents with chronic epigastric pain and a history of NSAID use for arthritis. Endoscopy reveals a gastric ulcer. Which is the most common site of peptic ulcer disease in the stomach?

Which pathogenic mechanism is responsible for NSAID-induced peptic ulcer disease?

A 48-year-old woman from Mumbai with a 10-year history of recurrent epigastric pain and dyspepsia is found to be Helicobacter pylori-positive on serology. What is the most common cause of peptic ulcer disease worldwide?