Tuberculosis Pathology

A 32-year-old man from rural Maharashtra presents with a 3-month history of cough, fever, and night sweats. Chest X-ray shows cavitary lesions in the right upper lobe. Sputum smear microscopy is positive for acid-fast bacilli. He has no prior TB treatment history and normal renal and hepatic function. What is the drug of choice as the backbone of his initial intensive phase regimen?

A 38-year-old man from rural Maharashtra presents with a 3-month history of productive cough, fever, and night sweats. Chest X-ray shows cavitary lesions in the right upper lobe. Sputum smear microscopy is positive for acid-fast bacilli (AFB). He has no prior TB history and no known HIV exposure. What is the most appropriate next step in management?

A 42-year-old woman with biopsy-proven pulmonary TB on standard HRZE therapy for 2 months reports persistent productive cough, fever, and weight loss. Repeat sputum smear microscopy remains positive for AFB. CXR shows no radiological improvement. She reports good adherence to medications. What is the most appropriate next step in management?

Which of the following is the hallmark histopathological feature of tuberculosis?

In primary tuberculosis, which lymph node group is most commonly involved as part of the Ghon complex?