Alpha Blockers

Which alpha blocker is selective for α1A receptors in the prostate and has minimal effect on vascular α1B receptors, making it the preferred agent for benign prostatic hyperplasia with minimal blood pressure reduction?

A 58-year-old man with benign prostatic hyperplasia (BPH) presents with nocturia (×4/night), weak urinary stream, and incomplete emptying. He has no contraindications to alpha blockers. Which drug is the preferred first-line alpha blocker for symptomatic BPH in this patient?

A 62-year-old man with hypertension and BPH is started on an alpha blocker. He develops severe orthostatic hypotension and syncope on the first dose. Which alpha blocker would be the safest alternative that minimizes first-dose syncope while still treating both conditions?

A 58-year-old man with benign prostatic hyperplasia (BPH) presents with lower urinary tract symptoms (LUTS). He is started on an alpha-1 blocker. Before initiating therapy, which investigation is most appropriate to exclude secondary causes of LUTS and assess baseline urinary function?

A 58-year-old man with benign prostatic hyperplasia presents with lower urinary tract symptoms. Which alpha blocker is the most commonly prescribed agent for this indication in clinical practice?