According to KDIGO classification, which of the following defines AKI Stage 2?

Question

Accepted Answer

D. Serum creatinine 2–2.9 times baseline or urine output <0.5 mL/kg/hr for ≥12 hours. ## KDIGO AKI Staging

**Key Point:** The KDIGO (Kidney Disease: Improving Global Outcomes) classification stratifies AKI into three stages based on both serum creatinine (SCr) and urine output criteria; the worse of the two determines the stage.

### KDIGO Stage Definitions

| Stage | Serum Creatinine Criterion | Urine Output Criterion |
|-------|---------------------------|------------------------|
| **Stage 1** | 1.5–1.9× baseline | <0.5 mL/kg/hr for 6–12 hrs |
| **Stage 2** | 2–2.9× baseline | <0.5 mL/kg/hr for ≥12 hrs |
| **Stage 3** | ≥3× baseline OR ≥4.0 mg/dL increase | <0.3 mL/kg/hr for ≥24 hrs OR anuria for ≥12 hrs |

**High-Yield:** Stage 2 specifically requires serum creatinine elevation of 2–2.9 times the baseline value OR oliguria (<0.5 mL/kg/hr) sustained for ≥12 hours. This intermediate stage carries higher mortality and morbidity than Stage 1 and warrants urgent intervention.

**Clinical Pearl:** The KDIGO system replaced the older RIFLE and AKIN classifications because it better predicts patient outcomes and is more widely adopted in clinical practice globally.

**Tip:** When staging AKI, always check BOTH SCr and urine output — use whichever criterion places the patient in the higher stage.

Answer

A. Serum creatinine 1.5–1.9 times baseline or urine output <0.5 mL/kg/hr for 6–12 hours

Answer

B. Serum creatinine ≥3 times baseline or increase ≥4.0 mg/dL or urine output <0.3 mL/kg/hr for ≥24 hours

Answer

C. Serum creatinine increase of any degree with oliguria lasting >48 hours

According to KDIGO classification, which of the following defines AKI Stage 2?

Explanation

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