A 42-year-old woman presents with acute-onset severe epigastric pain radiating to the back, vomiting, and fever. CECT abdomen shows pancreatic edema with peripancreatic stranding. The gross pathology specimen reveals chalky white spots within the pancreatic and peripancreatic fat, as marked B in the diagram. Which of the following best explains the pathophysiological mechanism underlying these chalky white lesions?

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