In BPH, urinary obstruction is present because of increased size of prostate(static component). This is increased by spasm of urethra(dynamic component).To dilate urethra; alpha 1A receptor blockers like tamsulosin and silodosin are used. These provide the immediate symptomatic relief by treating the dynamic component.To decrease the size of prostate, 5 alpha reductase inhibitors are used which inhibit the conversion of testosterone to DHT(dihydrotestosterone). Drugs are dutasteride and finasteride. These drugs are given for long duration.
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