Acetazolamide is given to a patient of angle closure glaucoma. It is a non-competitive inhibitor of carbonic anhydrase enzyme. Which of the following should be the effect of this drug?

Explanation

* Enzyme inhibition is of 3 types: Type of inhibition Km Vmax Competitive inhibition Increases No change Non competitive inhibition No change Decreases Uncompetitive inhibition Decreases Decreases * In question non competitive inhibitor is given, so answer is decrease in Vmax.