According to the latest guidelines treatment of multibacillary and paulibacillary leprosy is same expect for duration of treatment. Multibacillary Paulibacillary Rifampin 600 mg once a month supervised 600 mg once a month supervised Clofazimine 300 mg once a month supervised + 50 mg daily self administered 300 mg once a month supervised + 50 mg daily self administered Dapsone 100 mg daily self administered 100 mg daily self administered Duration 12 months 6 months
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