A 48-year-old man with chronic kidney disease (eGFR 35 mL/min/1.73m²) and hypertension develops progressive left ventricular hypertrophy. His serum potassium is 4.8 mEq/L and creatinine is 2.1 mg/dL. Which agent is the preferred first-line choice to promote LVH regression while providing renal protection?
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