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Subjects/Pharmacology/Chemotherapy

Chemotherapy

easy

pill Pharmacology

Which anti-cancer drug causes hemorrhagic cystitis as a characteristic adverse effect?

A. Cyclophosphamide

B. Methotrexate

C. Cisplatin

D. Vincristine

Explanation

Cyclophosphamide causes hemorrhagic cystitis due to its toxic metabolite acrolein. Prevention is by hydration and Mesna.

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