## Clinical Diagnosis: Acute Compartment Syndrome **Key Point:** Compartment syndrome is a surgical emergency requiring fasciotomy within 6–8 hours of symptom onset to prevent irreversible tissue necrosis and systemic complications. ### Classic Presentation The patient exhibits the **"5 P's"** of compartment syndrome: 1. **Pain** — out of proportion to clinical injury (most sensitive and earliest sign) 2. **Pain with passive stretch** — passive dorsiflexion causes severe pain (pathognomonic) 3. **Paresthesia** — diminished sensation over dorsum of foot (nerve ischemia) 4. **Pallor** — tense swelling (tissue edema) 5. **Pulselessness** — late finding; pulses may still be present early **High-Yield:** Preserved pulses do NOT exclude compartment syndrome. Arterial pressure exceeds compartment pressure initially; venous and capillary flow ceases first. ### Why Fasciotomy Is Urgent Compartment pressure rises rapidly after crush injury. Muscle becomes ischemic when compartment pressure approaches diastolic blood pressure. Irreversible damage occurs within 6–8 hours: - Muscle necrosis → rhabdomyolysis → hyperkalemia, myoglobinuria, acute kidney injury - Nerve ischemia → permanent sensorimotor deficit - Tissue loss → contracture and functional impairment **Clinical Pearl:** Fasciotomy should NOT be delayed for imaging (CT, MRI) or compartment pressure measurement in a clinically obvious case. Clinical diagnosis is sufficient. ### Why Other Options Fail | Option | Why Wrong | | --- | --- | | Elevation + ice | Conservative measures do not relieve compartment pressure; delays definitive treatment and allows irreversible damage. | | IV fluids + observation | Observation is contraindicated in acute compartment syndrome; 6 hours is already at the threshold of irreversibility. | | Amputation | Premature; fasciotomy preserves limb viability if performed urgently. Amputation is a last resort after failed fasciotomy or established gangrene. | **Warning:** Do not confuse compartment syndrome with simple crush injury or contusion. The key discriminator is pain out of proportion and pain with passive stretch. 
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