A 42-year-old woman from Mumbai with MDR-TB has completed 18 months of WHO-recommended MDR-TB therapy (fluoroquinolone, bedaquiline, linezolid, and amikacin). Repeat sputum smear microscopy and culture remain positive. DST on the latest isolate shows additional resistance to fluoroquinolones and bedaquiline. What is the most appropriate next step?

See the options, answer & explanation

Sign in free to reveal the answer choices, the correct answer, the detailed explanation, and AI-powered insights for this question.