A 62-year-old man presents with a 3-month history of rapidly progressive cognitive decline, myoclonus triggered by startle, and cerebellar ataxia. Brain MRI shows cortical ribboning and hyperintensity in the caudate and putamen on DWI sequences. His EEG is shown in the diagram. The pattern marked A — generalized periodic sharp wave complexes at 1 Hz — is characteristic of which of the following conditions?

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