## Fracture Healing Timeline and Radiological Correlation **Key Point:** Fracture healing progresses through overlapping but distinct phases; at 6 weeks post-fracture, the reparative phase with hard (bony) callus formation is the expected stage. ### Timeline of Fracture Healing Phases | Phase | Duration | Histology | Radiological Findings | Clinical Signs | |-------|----------|-----------|----------------------|----------------| | **Inflammatory** | 0–2 weeks | Haematoma, fibrin clot, inflammatory cells | Fracture line sharp, no callus | Pain, swelling, instability | | **Reparative (Soft Callus)** | 2–3 weeks | Fibrocartilaginous tissue, early woven bone | Soft tissue callus, indistinct margins | Decreasing pain, early stability | | **Reparative (Hard Callus)** | 3–8 weeks | Woven bone, lamellar bone deposition | Bridging callus, partial line obliteration | Weight-bearing tolerance, minimal tenderness | | **Remodelling** | 8 weeks–2 years | Conversion to lamellar bone, removal of excess callus | Callus resorption, normal architecture restoration | Full function, no tenderness | **High-Yield:** At 6 weeks, bridging callus with partial obliteration of the fracture line on X-ray is pathognomonic for the hard callus (late reparative) phase. ### Clinical Correlation in This Case - **Minimal tenderness** → callus has formed and provided mechanical stability - **Early weight-bearing tolerance** → sufficient hard callus present to support load - **Bridging callus on X-ray** → woven bone has crossed the fracture gap - **Partial line obliteration** → remodelling has begun but is incomplete **Clinical Pearl:** The transition from soft to hard callus occurs around week 3–4; by week 6, hard callus dominates. This patient is in the middle-to-late reparative phase, not yet in full remodelling (which takes months to years). **Mnemonic: FHIR** — **F**ibrocartilaginous (soft callus, 2–3 weeks) → **H**ard callus (3–8 weeks) → **I**nterstitial remodelling → **R**estoration (8 weeks–2 years). 
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