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    Subjects/Microbiology/Hepatitis B — Serology and Markers
    Hepatitis B — Serology and Markers
    medium
    bug Microbiology

    A 32-year-old man from Delhi presents with jaundice, dark urine, and abdominal discomfort for 2 weeks. He reports a history of needle-stick injury 6 months ago while working as a healthcare worker. On examination, he has hepatomegaly and mild splenomegaly. Liver function tests show ALT 1200 IU/L, AST 980 IU/L, and total bilirubin 4.2 mg/dL. His serological markers are: HBsAg positive, anti-HBs negative, anti-HBc IgM positive, HBeAg positive, anti-HBe negative. What is the most likely interpretation of these findings?

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