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    Subjects/Microbiology/Hepatitis B — Serology and Markers
    Hepatitis B — Serology and Markers
    medium
    bug Microbiology

    A 32-year-old man from Mumbai presents with jaundice, dark urine, and abdominal discomfort for 2 weeks. He reports a history of needle-stick injury 6 months ago while working as a healthcare worker. On examination, he is icteric with hepatomegaly. Liver function tests show ALT 2800 IU/L, AST 2200 IU/L, bilirubin 8.5 mg/dL. Serology reveals: HBsAg positive, anti-HBc positive, IgM anti-HBc positive, anti-HBs negative, HBeAg positive, anti-HBe negative. What is the most likely interpretation of these serological markers?

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