A 32-year-old immunocompromised man (CD4 count 45 cells/μL) presents with progressive vision loss, floaters, and retinal hemorrhages. Fundoscopy reveals a granular, hemorrhagic retinitis with a 'cottage cheese and ketchup' appearance. Which single laboratory or clinical finding best distinguishes this cytomegalovirus (CMV) retinitis from acute retinal necrosis (ARN) caused by HSV or VZV?

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