A 38-year-old woman from Mumbai presents with recurrent corneal opacities, hepatosplenomegaly, and progressive neurological decline over 2 years. Lipid profile shows total cholesterol 420 mg/dL, LDL 380 mg/dL, HDL 18 mg/dL, and triglycerides 95 mg/dL. Serum apolipoprotein B is markedly elevated. Genetic testing reveals a homozygous mutation in the LDLR gene. What is the primary mechanism of dyslipidemia in this patient?

See the options, answer & explanation

Sign in free to reveal the answer choices, the correct answer, the detailed explanation, and AI-powered insights for this question.

Daily MCQs, study tips, and topper strategies on Telegram.