A 35-year-old farmer from rural Uttar Pradesh presents with a 2-week history of fever, agitation, and hydrophobia following a dog bite 6 weeks ago. He did not receive post-exposure prophylaxis. Brain biopsy shows eosinophilic cytoplasmic inclusions within neurons. The structure marked D in the diagram is noted on histopathology. Which of the following statements about this finding is most accurate?

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