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    Subjects/Pathology/Paget Disease of Bone — Mosaic Cement Lines
    Paget Disease of Bone — Mosaic Cement Lines
    medium
    microscope Pathology

    A 68-year-old man of European descent presents with progressive bilateral femoral bowing and bone pain. Radiographs show a mixed lytic and sclerotic pattern in both femurs with cortical thickening and expanded bone diameter. Bone biopsy reveals the characteristic **A** — an irregular pattern of cement lines with admixed lamellar and woven bone. Which of the following best explains the histologic finding at **A**?

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