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    Subjects/Biochemistry/Pentose Phosphate Pathway
    Pentose Phosphate Pathway
    medium
    flask-conical Biochemistry

    A 28-year-old Indian male presents to the emergency department with acute haemolytic anaemia following ingestion of fava beans at a wedding feast. Laboratory investigations reveal haemoglobin 7.2 g/dL, reticulocyte count 8%, elevated indirect bilirubin, and reduced haptoglobin. Peripheral blood smear shows bite cells and Heinz bodies. Enzyme assay confirms glucose-6-phosphate dehydrogenase (G6PD) deficiency. Which of the following best explains the acute haemolysis in this patient?

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