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Subjects/Pharmacology/Pharmacology
Pharmacology
medium
pill Pharmacology

Vasopressin antagonist acts on which pa of the nephron?

A. Proximal convoluted tubule
B. Distal convoluted tubule
C. Coical collecting tubule
D. Medullary collecting duct

Explanation

Answer- D (Medullary collecting duct)'The mechanism by which vasopressin exes its anti-diuretic effect is activated by V2 receptors and involves the inseion of aquaporin-2 into the apical (luminal) membranes at the principle cells of the collecting duct.'

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