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Subjects/Pharmacology/Pharmacology
Pharmacology
medium
pill Pharmacology

Compared to unfractionated heparin, Low molecular weight heparin (LMWH) has reliable anticoagulant action because:

A. It interferes with thrombin and antithrombin III simultaneously
B. It is less protein bound
C. It is given subcutaneously
D. It is cleared by macrophages

Explanation

Answer- B. It is less protein boundCompared to unfractionated heparin, Low molecular weight heparin (LMWH) has reliable anticoagulant action because it is less protein bound.Indications of LMW heparins:Prophylaxis of DVT and pulmonary embolism in high-risk patients undergoing surgery stroke or other immobilized patientsTreatment of established DVTUnstable anginaTo maintain patency of cannulae and shunts in dialysis patients and in extracorporeal circulation.

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