A 58-year-old man from rural Maharashtra presents to a primary health centre with acute onset chest pain of 2 hours duration. He describes the pain as crushing in nature, radiating to the left arm and jaw. On examination, blood pressure is 95/60 mmHg, heart rate 108/min, and he is diaphoretic. A 12-lead ECG obtained within 10 minutes shows ST elevation of 3 mm in leads II, III, and aVF, with reciprocal ST depression in leads I and aVL. Troponin I is 0.08 ng/mL (normal <0.04). The nearest PCI-capable centre is 120 km away with an estimated transfer time of 2.5 hours. What is the most appropriate immediate management?