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    SubjectsDermatologyAcanthosis Nigricans Insulin Resistance
    ClinicalDermatology

    Acanthosis Nigricans Insulin Resistance

    1 MCQs in Dermatology for NEET PG

    1 Medium
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    Sample Questions

    medium

    A 42-year-old woman with a BMI of 34 kg/m² presents to the dermatology clinic with a 6-month history of progressive darkening and thickening of the skin over her neck, armpits, and groin folds. On examination, the affected areas show symmetric, hyperpigmented, velvety plaques as marked **A** in the diagram. Laboratory investigations reveal fasting glucose 118 mg/dL, fasting insulin 22 mIU/L (normal <12), and HbA1c 6.8%. Which of the following best explains the pathophysiology of the cutaneous lesion marked **A**?

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