Candidiasis — Mucocutaneous

A 28-year-old woman presents with white patches on her tongue and inner cheeks that do not scrape off easily. She has a history of poorly controlled type 2 diabetes (HbA1c 9.2%) and has been on broad-spectrum antibiotics for a respiratory tract infection for the past 3 weeks. On examination, the patches are erythematous and painful when touched. KOH mount of the scraped material shows pseudohyphae and budding yeast. What is the most appropriate initial management?

A 35-year-old woman with a 10-year history of systemic lupus erythematosus (SLE) on chronic corticosteroids (prednisolone 15 mg daily) presents with recurrent episodes of vulvovaginal candidiasis over the past 6 months. She reports itching, burning, and thick white vaginal discharge. Wet mount microscopy shows budding yeast and pseudohyphae. She has completed three courses of topical clotrimazole cream over 2 months with only temporary relief. What is the most appropriate next step?

A 35-year-old woman with poorly controlled type 2 diabetes mellitus presents with erythema, maceration, and white plaques in her vulvovaginal region. She reports pruritus and vaginal discharge for 1 week. She denies fever or systemic symptoms. Wet mount microscopy shows pseudohyphae and budding yeast. She has had two similar episodes in the past 6 months. Which of the following is the BEST initial step in her management?

A 28-year-old woman presents with white plaques on her tongue and inner cheeks that are painful and interfere with eating. She reports a 2-week history of these lesions. She is otherwise healthy, denies fever, and has no significant past medical history. On examination, the plaques are adherent and cannot be wiped off easily. Oral candidiasis is suspected. Which of the following is the most appropriate initial management?