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    SubjectsDermatologyPellagra — The 4 Ds and Casal Necklace
    ClinicalDermatology

    Pellagra — The 4 Ds and Casal Necklace

    1 MCQs in Dermatology for NEET PG

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    Sample Questions

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    A 48-year-old man with a 20-year history of alcohol dependence presents to the dermatology clinic with a 3-week history of watery diarrhea, progressive apathy, and a striking symmetric, sharply demarcated hyperpigmented scaly dermatitis. On examination, he has a broad necklace-shaped rash across the anterior neck and upper chest, with matching lesions on the dorsa of the hands and forearms in a "gauntlet" distribution. The condition marked **B** in the diagram is suspected. Which of the following biochemical defects BEST explains the pathophysiology of this condition?

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