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    SubjectsENTAudiogram — Alport Syndrome High-Frequency SNHL + Hematuria
    ClinicalENT

    Audiogram — Alport Syndrome High-Frequency SNHL + Hematuria

    1 MCQs in ENT for NEET PG

    1 Medium
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    A 16-year-old boy presents with persistent microscopic hematuria detected on routine urinalysis. Audiometry shows bilateral symmetric sensorineural hearing loss beginning at 2 kHz and sloping downward, as marked **A** in the diagram. Renal biopsy electron microscopy reveals alternating thinning and thickening of the glomerular basement membrane with a characteristic basket-weave appearance. Which of the following best explains the pathophysiology of this patient's hearing loss?

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