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    SubjectsENTCisplatin Ototoxicity
    ClinicalENT

    Cisplatin Ototoxicity

    1 MCQs in ENT for NEET PG

    1 Medium
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    Sample Questions

    medium

    A 46-year-old woman with stage III locally advanced cervical cancer is undergoing concurrent chemoradiation with weekly cisplatin (40 mg/m²). After her 4th cycle (cumulative dose ~160 mg/m²), she develops bilateral tinnitus and difficulty understanding speech in noisy environments. Otoscopy is normal, Weber does not lateralize, and Rinne is positive bilaterally. Pure-tone audiometry demonstrates the pattern marked **A** in the diagram. Which of the following best explains the pathophysiology of this hearing loss pattern?

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