Laryngeal Carcinoma

A 58-year-old male smoker presents with hoarseness of voice for 3 months. Laryngoscopy reveals a 2 cm exophytic lesion on the left vocal cord with no evidence of distant metastases. Biopsy confirms squamous cell carcinoma. CT chest shows no involvement of anterior commissure or subglottis. What is the drug of choice for induction chemotherapy in this patient with locally advanced laryngeal carcinoma?

A 58-year-old male smoker presents with progressive hoarseness and stridor. Laryngoscopy reveals a large mass involving the anterior commissure with fixation of the vocal cord. Which feature best distinguishes glottic carcinoma from supraglottic carcinoma in this patient?

A 58-year-old male smoker with a 3-month history of progressive hoarseness and dysphagia is found to have a left vocal cord lesion on laryngoscopy. Biopsy confirms squamous cell carcinoma. All of the following are appropriate components of staging and management EXCEPT:

A 58-year-old male smoker presents with a 3-month history of progressive hoarseness and throat pain. He reports occasional dysphagia and a sensation of a lump in the throat. On laryngoscopy, a unilateral, irregular, ulcerated lesion is seen on the left vocal cord extending to the anterior commissure. There is no stridor. CT neck shows a 2 cm lesion confined to the larynx with ipsilateral level II lymph node enlargement (1.5 cm). Which TNM stage would this patient be classified as?

A 62-year-old male with a 40 pack-year smoking history presents with progressive dysphagia and a palpable left neck mass. Laryngoscopy shows a large lesion in the false vocal cord region. Which histopathological and clinical feature best distinguishes supraglottic squamous cell carcinoma from glottic squamous cell carcinoma?