1 MCQs in Pediatrics for NEET PG
A 3-year-old boy is brought to the pediatric clinic for evaluation of short stature. On examination, he has a height of 85 cm (well below the 3rd percentile for age), frontal bossing, midface hypoplasia, and trident hand deformity. Radiographs show the characteristic appearance marked as **A** in the diagram — squared iliac wings with a narrow sacrosciatic notch and horizontal acetabular roofs. Genetic testing confirms a de novo FGFR3 mutation (G380R). Which of the following best describes the pathophysiologic mechanism by which the pelvic changes marked **A** develop in achondroplasia?
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