1 MCQs in Pediatrics for NEET PG
A 9-year-old boy presents with pallor, bone pain, fevers, and fatigue. Examination reveals hepatosplenomegaly, cervical lymphadenopathy, and petechiae. CBC shows WBC 32,000/µL with 78% lymphoblasts, hemoglobin 6.9 g/dL, and platelets 28,000/µL. Flow cytometry confirms B-cell precursor ALL (CD10+, CD19+, CD22+, TdT+). Cytogenetic analysis reveals the karyotype shown at **B** with only 32 chromosomes per cell. Which of the following best characterizes the prognostic significance and molecular features of this cytogenetic finding?
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