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    SubjectsPediatricsPedigree — Sickle Cell Disease + Trait Heterozygous
    ClinicalPediatrics

    Pedigree — Sickle Cell Disease + Trait Heterozygous

    1 MCQs in Pediatrics for NEET PG

    1 Medium
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    Sample Questions

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    A 28-year-old Indian woman with sickle cell trait (HbAS) presents for genetic counseling before planning pregnancy. Her partner has normal hemoglobin (HbAA). The pedigree diagram shows the inheritance pattern when one parent carries the sickle trait and the other has normal hemoglobin. The label **D** indicates the outcome that "No Affected (SS) Offspring When Only One Parent is Carrier." Based on this inheritance pattern, what is the most important counseling point regarding the risk of sickle cell disease (HbSS) in their children?

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