1 MCQs in Pediatrics for NEET PG
A 18-month-old boy presents with severe growth retardation (height −3.2 SD), relative macrocephaly (head circumference −0.5 SD), prominent forehead, and triangular facies with micrognathia. Birth weight was −2.8 SD for gestational age. Genetic testing reveals the abnormality marked **A** in the diagram. Which of the following best explains the pathophysiology of growth failure in this patient?
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