2 MCQs in Pharmacology for NEET PG
Which of the following microtubule inhibitors acts by stabilizing microtubules and preventing their depolymerization?
A 58-year-old man with newly diagnosed metastatic non-small-cell lung cancer (NSCLC) is planned for first-line chemotherapy. He has a history of severe constipation and bowel obstruction 2 years ago (managed medically). His baseline hemoglobin is 9.2 g/dL and platelets are 95,000/μL. The oncologist is choosing between paclitaxel and docetaxel as the microtubule inhibitor component. Which toxicity profile would MOST favor the choice of paclitaxel over docetaxel in this patient?
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