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    SubjectsPhysiologyPancreatic β-Cell Insulin Secretion
    Pre-clinicalPhysiology

    Pancreatic β-Cell Insulin Secretion

    1 MCQs in Physiology for NEET PG

    1 Hard
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    Sample Questions

    hard

    A 6-month-old male infant from rural Maharashtra presents with severe hypoglycemia (blood glucose 28 mg/dL) and seizures. Genetic testing reveals a heterozygous activating mutation in KCNJ11 (K-ATP channel gene). The structure marked **B** in the diagram is defective — the mutant channels remain constitutively open despite elevated intracellular ATP. Which of the following is the most appropriate initial pharmacological management?

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