1 MCQs in Radiology for NEET PG
A 58-year-old man presents with 6 weeks of progressive frontal headaches, personality change (apathy and disinhibition), and left-sided weakness. Examination reveals MMSE 23/30, left pronator drift, hyperreflexia, and bilateral papilledema. MRI brain with contrast is shown. The structure marked **B** demonstrates a heterogeneous mass with thick irregular rim enhancement, central necrosis, and marked vasogenic edema. MR spectroscopy shows elevated choline-to-NAA ratio (>2) and increased lipid-lactate peaks. Stereotactic biopsy confirms WHO Grade 4 glioblastoma, IDH-wildtype, with unmethylated MGMT promoter. Which of the following is the MOST appropriate initial management strategy for this patient?
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