1 MCQs in Surgery for NEET PG
A 28-year-old Indian woman presents for genetic counseling. Her father died of diffuse gastric cancer at age 52, and her paternal grandmother had lobular breast carcinoma at age 65. Genetic testing reveals a germline mutation in the structure marked **A** in the diagram. Which of the following best explains why endoscopic surveillance with random biopsies is considered inadequate for this patient despite annual screening?
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