ClinicalAnesthesia

Patient-Controlled Analgesia in Opioid-Maintained Patients

1 MCQs in Anesthesia for NEET PG

1 Hard

Sample Questions

hard

A 45-year-old male with a history of opioid use disorder (in remission for 2 years on buprenorphine maintenance) undergoes open abdominal surgery. Postoperatively, he is prescribed patient-controlled analgesia (PCA) with morphine. Within 2 hours of initiation, he develops acute respiratory depression (RR 8/min, SpO₂ 88%) and severe sedation. Which of the following is the MOST likely mechanism underlying this adverse event?

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